| 1 | Luis Suárez
Inter Miami CF | Inter Miami CF | 8 | 6 |
| - | Christian Benteke
D.C. United | D.C. United | 6 | 6 |
| - | Dejan Joveljic
LA Galaxy | LA Galaxy | 8 | 6 |
| - | Lewis Morgan
New York Red Bulls | New York Red Bulls | 8 | 6 |
| - | Cristian Arango
Real Salt Lake | Real Salt Lake | 8 | 6 |
| 6 | Georgios Giakoumakis
Atlanta United FC | Atlanta United FC | 4 | 5 |
| - | Lionel Messi
Inter Miami CF | Inter Miami CF | 5 | 5 |
| 8 | Dániel Gazdag
Philadelphia Union | Philadelphia Union | 6 | 4 |
| - | Raúl Ruidíaz
Seattle Sounders FC | Seattle Sounders FC | 7 | 4 |
| - | Julian Carranza
Philadelphia Union | Philadelphia Union | 6 | 4 |
| - | Evander
Portland Timbers | Portland Timbers | 6 | 4 |
| - | Rafael Navarro
Colorado Rapids | Colorado Rapids | 8 | 4 |
| 13 | Felipe Mora
Portland Timbers | Portland Timbers | 4 | 3 |
| - | Jamal Thiaré
Atlanta United FC | Atlanta United FC | 5 | 3 |
| - | Fafà Picault
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 6 | 3 |
| - | Mikael Uhre
Philadelphia Union | Philadelphia Union | 6 | 3 |
| - | William Agada
Sporting Kansas City | Sporting Kansas City | 7 | 3 |
| - | Matías Cóccaro
CF Montréal | CF Montréal | 7 | 3 |
| - | Prince-Osei Owusu
Toronto FC | Toronto FC | 8 | 3 |
| - | Duncan McGuire
Orlando City SC | Orlando City SC | 6 | 3 |
| - | Brian White
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 6 | 3 |
| - | Brian Gutiérrez
Chicago Fire FC | Chicago Fire FC | 8 | 3 |
| - | Cucho
Columbus Crew SC | Columbus Crew SC | 6 | 3 |
| - | Ibrahim Aliyu
Houston Dynamo FC | Houston Dynamo FC | 7 | 3 |
| - | Yuya Kubo
FC Cincinnati | FC Cincinnati | 8 | 3 |
| - | Carles Gil
New England Revolution | New England Revolution | 7 | 3 |
| - | Antony
Portland Timbers | Portland Timbers | 8 | 3 |
| - | Joseph Paintsil
LA Galaxy | LA Galaxy | 8 | 3 |
| - | Mateusz Bogusz
Los Angeles FC | Los Angeles FC | 8 | 3 |
| - | Erik Thommy
Sporting Kansas City | Sporting Kansas City | 8 | 3 |
| - | Santiago Rodríguez
New York City FC | New York City FC | 8 | 3 |
| - | Timothy Tillman
Los Angeles FC | Los Angeles FC | 8 | 3 |
| - | Cole Bassett
Colorado Rapids | Colorado Rapids | 8 | 3 |
| - | Denis Bouanga
Los Angeles FC | Los Angeles FC | 8 | 3 |
| 35 | Tani Oluwaseyi
Minnesota United FC | Minnesota United FC | 7 | 2 |
| - | Bongokuhle Hlongwane
Minnesota United FC | Minnesota United FC | 5 | 2 |
| - | Teal Bunbury
Nashville SC | Nashville SC | 6 | 2 |
| - | Guilherme Biro
Austin FC | Austin FC | 8 | 2 |
| - | Samuel Adeniran
St. Louis CITY SC | St. Louis CITY SC | 7 | 2 |
| - | Lorenzo Insigne
Toronto FC | Toronto FC | 5 | 2 |
| - | Leonardo Campana
Inter Miami CF | Inter Miami CF | 7 | 2 |
| - | Ryan Raposo
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 7 | 2 |
| - | Sam Surridge
Nashville SC | Nashville SC | 5 | 2 |
| - | Sebastian Driussi
Austin FC | Austin FC | 5 | 2 |
| - | Patrick Agyemang
Charlotte FC | Charlotte FC | 7 | 2 |
| - | Josef Martínez
CF Montréal | CF Montréal | 7 | 2 |
| - | Jacen Russell-Rowe
Columbus Crew SC | Columbus Crew SC | 6 | 2 |
| - | Vítor Costa
San Jose Earthquakes | San Jose Earthquakes | 7 | 2 |
| - | Jeremy Ebobisse
San Jose Earthquakes | San Jose Earthquakes | 8 | 2 |
| - | Robin Lod
Minnesota United FC | Minnesota United FC | 6 | 2 |